17th International Conference of the Society of Neuroscientists of Africa Marrakesh-Morocco April, 17-20, 2025

Title: Emerging regenerative medicine for CNS repair
Organizer: Fatiha Nothias & Afsaneh Gaillard
CNRS UMR8246/Inserm U1130, Sorbonne Université, Paris
INSERM U1084, Experimental and Clinical Neurosciences Laboratory, University of Potiers
email: fatiha.nothias@upmc.fr; afsaneh.gaillard@univ-poitiers.fr

Abstract:

In humans, traumatic, neurovascular, and neurodegenerative diseases have significant social consequences and can lead to life-long disability. This is due to the limited ability of the adult CNS for self-repair after injury, also linked to the complexity of these progressive diseases. This symposium will focus on recent progresses in CNS repair, addressing challenges such as limited axonal regeneration, poor revascularization, scarring, demyelination, and chronic inflammation. Despite the lack of available effective treatments, research is making progress in areas like immune modulation, axon regeneration, remyelination, and cell-based therapies. Physical activity-based therapies and neuromodulation, that reached the clinical practice, have also shown promise in re-establishing neuronal networks, further advancing neuro-restoration efforts. This symposium will bring together leading experts to provides a comprehensive overview of the current challenges and advancements in CNS repair. As the field progresses, it will also emphasize on the combination of approaches with cutting-edge technologies such as bioengineering, stem cell therapies and neuromodulation that offer great potential for CNS repair solutions in the near future: I. Loubinoux, will describe the effect of "Regenerative implants in Stroke and TBI"; A. Gaillard, will share her recent data on combined strategies to treat TBI in animal models; "Stem cells and biomaterial-based regenerative therapeutic strategies for the treatment of cortical injury"; I. Vivodtzev, will talk about Combinatorial therapies to improve respiratory recovery after cervical SCI: from bedside to pre-clinical studies and back to human translation; the title will be "Neurostimulation and respiratory recovery after cervical spinal cord injury"; J. Martin, will describe the advantage of "Combining Biomaterial Scaffold and Neuromodulation Strategy to Promote Tissue Repair and Corticospinal Connectivity after Spinal Cord Injury"; Finally, Neuromodulation has emerged as a promising therapeutic approach for managing symptoms of Parkinson's disease; thus A. Benazzouz will give us "An update on the pathophysiology and treatment of Parkinson's disease".

Speakers

Number	Speaker	e-mail	Title of  the communication
SP13_1	Abdelhamid Benazzouz	abdelhamid.benazzouz@u-bordeaux.fr	Neuromodulation and an update on the pathophysiology and treatment of Parkinson's disease
SP13_2	Isabelle Loubinoux	isabelle.loubinoux@inserm.fr	Regenerative implants in Stroke and TBI
SP13_3	Afsaneh Gaillard	afsaneh.gaillard@univ-poitiers.fr	Combination of biomaterial and stem cell-based strategies to improve cortical repair
SP13_4	Isabelle Vivodtzev	isabelle.vivodtzev@sorbonne-universite.fr	Neurostimulation and respiratory recovery after cervical spinal cord injury
SP13_5	John Jack H Martin	jmartin@med.cuny.edu	Combined Biomaterial Scaffold and Neuromodulation Strategy to Promote Tissue Repair and Corticospinal Connectivity after Cervical Spinal Cord Injury.