 17th
International Conference of the Society of Neuroscientists of Africa Marrakesh-Morocco April, 17-20, 2025 |
Symposium
22
Title: The Brain, Environment and
Nutraceuticals; Combating Neurodegeneration through Neuroprotection
Organizer: Abel N. Agbon
Neuroanatomy and Neuroscience Research Unit, Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Medical Sciences, Ahmadu Bello University, Zaria, Nigeria
email: bellulu@gmail.com
Abstract:
| The brain is an integral part of
a biological system involved in the homeostasis of several vital
functions. Exposure to environmental neurotoxins have been associated
with neurodegenerative disease conditions including Alzheimer's and
Parkinson's disease that are characterized by progressive structural,
biochemical and physiological alterations in different brain parts
critically associated with motor and cognitive functions.
Nutraceuticals, especially plants-derived, have been reported as
potential therapies for the management or treatment of neurological
disease conditions. A promising strategy for the management and therapy of neurodegenerative diseases is the targeting of multiple mechanisms of actions associated with the pathologies of neurodegeneration through neuroprotective approach. A.N. Agbon will focus his talk on the neuroprotective activity of Phoenix dactylifera (date palm) on mercury-triggered neurodegenerative changes in animal model. S.B. Mesole will explain the neuroprotective effects of Eugenol following aluminium-induced neurotoxicity on caspase-3, apoptotic proteins (Bcl-2 and Bax), oxidative stress biomarkers and levels of 8-hydroxy-2-deoxyguanosine (mitochondrial DNA stress marker) in animal model. Then, FSA Yadang will focus her talk on the neuroprotective activity of Carissa edulis against L-glutamic acid-induced oxidative stress, inflammation, and memory impairment in animal model and, Rachael Henry will discuss the neuroprotective properties of flavonoid fraction of P. dactylifera on rotenone model of Parkinson's disease in animal model. |
Speakers
| Number |
Speaker |
e-mail |
Title
of the communication |
| SP22_1 |
Abel N. Agbon |
bellulu@gmail.com | Phoenix
dactylifera (date palm) has Neuroprotective Activity on
Mercury-triggered Neurodegenerative Changes in Wistar rats |
| SP22_2 |
Samuel B. Mesole |
ms361450@gmail.com | Apoptotic
Inducement of Neuronal Cells by Aluminium Chloride and The
Neuroprotective Effects of Eugenol in Wistar rats. |
| SP22_3 |
Fanta S.A. Yadang | fantayadang@gmail.com |
Protective effect
of Carissa edulis aqueous extract against L-glutamic acid-induced
neurotoxicity in mice by regulating oxidative stress and
neuroinflammation |
| SP22_4 |
Rachael
Henry |
henryrachel99@gmail.com |
Neuroprotective Efficacy of
Phoenix dactylifera L. in rotenone rat model of Parkinson's Disease |