 17th
International Conference of the Society of Neuroscientists of Africa Marrakesh-Morocco April, 17-20, 2025 |
Symposium
24
Title: Management of Neurodegenerative
Disorders by Potential Bioactive Compounds
Organizer: Olfa Masmoudi & Taoufik Ghrairi
University Tunis el Manar, Tunisia
email: taoufik.ghrairi@fst.utm.tn; olfa.masmoudi@fst.utm.tn
Abstract:
| Neurodegenerative disorders,
including Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD), and Lewy body dementia (LBD), affect
millions worldwide, leading to significant mental and physical
disabilities as well as and socio-economic burdens on the population.
While most of these diseases are closely linked to aging and share
common aging-related biological features, they are also driven by
cellular stress, resulting in biochemical alterations like abnormal
protein aggregation, excessive production of reactive oxygen and
nitrogen species, mitochondrial dysfunction, and neuroinflammation, all
of which can damage brain cells. Neuroprotective strategies typically focus on therapies that promote cell survival pathways and rehabilitation methods aimed at enhancing the brain’s repair mechanisms or inhibiting cell death processes, thereby strengthening neurons' ability to resist disease. Recent advances have identified critical pathways and targets associated with neurodegenerative diseases and neuroprotection. This symposium highlights groundbreaking research for neurodegenerative disorders and offers various perspectives for advancing neuroprotective therapies. |
Speakers
| Number |
Speaker |
e-mail |
Title
of the communication |
| SP24_1 |
Taoufik GHRAIRI |
taoufik.ghrairi@fst.utm.tn | A Proteomic Analysis to Study Neuroprotective Bioactivity of Essential Oil |
| SP24_2 |
Olfa Masmoudi |
olfa.masmoudi@fst.utm.tn | Protective and Neurotrophic Effects of OctaDeca Neuropeptide (ODN) in in vitro and in vivo models of neurodegenerative diseases |
| SP24_3 |
Amira Zaky | amzakyha@yahoo.com |
Implication of differential targeting of key cellular modulators in pain management. |
| SP24_4 |
Gérard
Lizard |
Gerard.Lizard@u-bourgogne.fr |
Implication of cholesterol oxidation products (oxysterols) in neurodegeneration: cytoprotective activities of polyphenols, tocopherols and fatty acids, representative nutrients of the Mediterranean diet |