 17th
International Conference of the Society of Neuroscientists of Africa Marrakesh-Morocco April, 17-20, 2025 |
Symposium
9
Title: Emerging effectors in neurodegeneration: from preclinical
to clinical models
Organizer: Ines Elbini
Institut Pasteur de Tunis, Tunisia
email: ines.bini@pasteur.tn
Abstract:
| This symposium explores the
impact of emerging effectors such as ion channels, receptors, and
cytokines on neurodegeneration within preclinical and clinical models.
A particular emphasis will be placed on the underlying
pathophysiological mechanisms driving these processes. The symposium
will be chaired by a panel of scientists from the Institut Pasteur of
Tunis (IPT), Tunisia and UM6P, Morocco. Dr. Rym Benkhalifa will
elucidate the of the Kv3.1 potassium channel in specific
pathophysiological conditions and recount the process of investigating
this channel within the context of her research team's work. Dr. Amani
Cheikh, will examine the role of nicotinic receptors in
neurodegeneration. Dr. Meriam Belghith, will tackle the practical
challenges in understanding the molecular mechanisms of
neuroinflammation, a critical aspect of neurodegeneration. Finally, Dr.
Mohamed Taha Moutaoufik from UM6P will explore systems biology
approaches to understand mitochondrial functions and their implications
in neurodegenerative diseases, with a particular focus on Parkinson's
disease. Together, these presentations will offer a comprehensive
overview of emerging effectors that could serve as potential targets
for future therapeutic strategies, utilizing either natural or chemical
molecules. This symposium aims to provide fresh insights into
neurodegenerative diseases management, by highlighting innovative
approaches to counteract the pathophysiological mechanisms at play. Symposium Speakers: 1- When the secondary role plays its full part: the story of the Kv3.1 channel in neuropathologies (Rym Benkhalifa - Tunisia) 2- Key role of Nicotinic receptors in neurodegeneration : Promising therapeutic targets for new treatments (Amani Cheikh, Tunisia) 3- Title: Adaptive immune cells in the cerebrospinal fluid of neuroinflammatory disorders:The control of cytokine production (Meriam Belghith- Tunisia) 4- Title: Decoding Mitochondrial Interactomes: Insights into Neurodegenerative Disease Mechanisms (Mohamed Taha Moutaoufik - Morocco). |
Speakers
| Number |
Speaker |
e-mail |
Title
of the communication |
| SP9_1 |
Rym Benkhalifa |
rymbkh@gmail.com | When the secondary role plays its full part: the story of the Kv3.1 channel in neuropathologies. |
| SP9_2 |
Amani Cheikh |
cheikhamani@gmail.com | KEY ROLE OF NICOTINIC RECEPTORS IN NEURODEGENERATION : PROMISING THERAPEUTIC TARGETS FOR NEW TREATMENTS. |
| SP9_3 |
Meriam Belghith | belghith.meriam@gmail.com |
Adaptive immune cells in the cerebrospinal fluid of neuroinflammatory disorders:The control of cytokine production. |
| SP9_4 |
Mohamed
Moutaoufik |
mohamed.moutaoufik@um6p.ma |
Mitochondrial Interactomes and Neurodegenerative Disease Mechanisms |